We actively collaborate with healthcare professionals and institutions who wish to contribute to the further development of the Artimis® Meniscus Prosthesis. The input of our clinical partners is essential in optimizing the prosthesis and ensuring it is closely aligned with the needs of patients.
Artimis® is a meniscus prosthesis specifically developed for patients with persistent knee pain following meniscectomy in whom previous treatments have proven insufficient. The prosthesis offers a less invasive alternative compared to procedures such as corrective osteotomy or meniscus allograft transplantation.
The Artimis® Meniscus Prosthesis is designed to help reduce pain and improve mobility, thereby addressing an unmet need within the current range of surgical treatment options for meniscus patients. Our mission is to enable people with meniscal pathology to move better and with less pain.
ATRO Medical collaborates with leading medical centers in the Netherlands to investigate the Artimis® Meniscus Prosthesis. The safety and effectiveness of the implant are currently being evaluated in clinical studies in collaboration with:
St. Maartenskliniek, Nijmegen
Maastricht UMC+, Maastricht
Radboudumc, Nijmegen
ATRO Medical actively welcomes feedback and seeks close cooperation with the international knee community. Experts from Europe, Japan, and the United States contribute to discussions on patient indication, surgical technique, and reimbursement pathways. This valuable input supports the ongoing development of the Artimis® Meniscus Prosthesis and accelerates the translation of research findings into clinical practice.
Orthopedic surgeons may be involved in our studies in various roles, including as operating surgeons, members of the independent safety monitoring committee, or advisors on our Scientific Advisory Board. Many of these contributors are knee surgeons with extensive experience in meniscus and cruciate ligament surgery.
The Artimis® Meniscus Prosthesis is intended for patients who experience chronic knee pain after partial or total meniscectomy and who do not have advanced cartilage degeneration (Modified Outerbridge grade 1–3). Patients between 18 and 70 years of age may be eligible for study participation, provided they have undergone conservative treatment without sufficient symptom relief and have relatively neutral lower limb alignment (<5° varus or valgus).
The procedure is performed arthroscopically, during which residual meniscal tissue is removed and two tunnels are created in the tibia.
Procedure time: approximately 1 hour
Primary objective: clinical improvement in pain scores within 1 year, measured using the KOOS pain subscale
Rehabilitation: 3–6 months under the supervision of a physiotherapist
The Artimis® Meniscus Prosthesis is currently being evaluated in multiple clinical studies:
EARTH study (lateral prosthesis) – open for enrollment
AIR2 study (medial prosthesis) – enrollment closed
AIR study (medial prosthesis) – completed
Are you an arthroscopic knee surgeon and interested in learning more about the Artimis® Meniscus Prosthesis? Please contact us by the form below.
Van Minnen BS, van Tienen TG. The Current State of Meniscus Replacements. Curr Rev Musculoskelet Med. (2024) PMID: 38744802. https://pubmed.ncbi.nlm.nih.gov/38744802/
Van Tienen TG, van Minnen B, Defoort KC, Emans PJ, van de Groes SAW, Verdonschot N, Jutten LM, Pikaart RWE, Heesterbeek PJC; The first-generation anatomical medial meniscus prosthesis led to unsatisfactory results: a first-in-human study. Knee Surg Sports Traumatol Arthrosc. (2023) ;31(6):2526-2533. https://pubmed.ncbi.nlm.nih.gov/36336744/
Van Minnen BS, van der van der Veen AJ, van de Groes SAW, Verdonschot NJJ, van Tienen TG; An anatomically shaped medial meniscus prosthesis is able to partially restore the contact mechanics of the meniscectomized knee joint; J Exp Orthop. (2022), 9(1):91.https://pubmed.ncbi.nlm.nih.gov/36071256/
Vrancken ACT, Hannink G, Madej W, Verdonschot N, van Tienen TG, Buma P; In Vivo Performance of a Novel, Anatomically Shaped, Total Meniscal Prosthesis Made of Polycarbonate Urethane: A 12-Month Evaluation in Goats. Am J Sports Med. (2017), 45(12):2824-2834. https://pubmed.ncbi.nlm.nih.gov/28719787/
Vrancken ACT, Eggermont F, van Tienen TG , Hannink G, Buma P, Janssen D, Verdonschot N; Functional biomechanical performance of a novel anatomically shaped polycarbonate urethane total meniscus replacement; Knee Surg Sports Traumatol Arthrosc. (2016), 24:1485-1494. https://pubmed.ncbi.nlm.nih.gov/25971457/
Khoshgoftar M, Vrancken ACT, Janssen D, van Tienen TG , Buma P, Verdonschot N; The sensitivity of cartilage contact pressures in the knee joint to the size and shape of an anatomically shaped meniscal implant; Journal of Biomechanics (2015), 48(8):1427-1435. https://pubmed.ncbi.nlm.nih.gov/25766390/
Vrancken ACT, van Tienen TG , Hannink G, Janssen D, Verdonschot N, Buma P; Releasing the circumferential fixation of the medial meniscus does not influence its kinematics; The Knee (2014), 21:1033-1038. https://pubmed.ncbi.nlm.nih.gov/25262847/